As Voltaire put it in his Memnon, "our little terraqueous globe is the madhouse of those hundred thousand millions of worlds." We, who cannot even put our own planetary home in order, riven with rivalries and hatreds, despoiling our environment, murdering one another through irritation and inattention as well as on deadly purpose, and moreover a species that until only recently was convinced that the Universe was made for its sole benefit — are we to venture out into space, move worlds, reengineer planets, spread to neighboring star systems?
I do not imagine that it is precisely we, with our present customs and social conventions, who will be out there. If we continue to accumulate only power and not wisdom, we will surely destroy ourselves. Our very existence in that distant time requires that we will have changed our institutions and ourselves. How can I dare to guess about humans in the far future? It is, I think, only a matter of natural selection. If we become even slightly more violent, shortsighted, ignorant, and selfish than we are now, almost certainly we will have no future.
If you're young, it's just possible that we will be taking our first steps on near-Earth asteroids and Mars during your lifetime. To spread out to the moons of the Jovian planets and the Kuiper Comet Belt will take many generations more. The Oort Cloud will require much longer still. By the time we're ready to settle even the nearest other planetary systems, we will have changed. The simple passage of so many generations will have changed us. The different circumstances we will be living under will have changed us. Prostheses and genetic engineering will have changed us. Necessity will have changed us. We're an adaptable species.
Carl Sagan
1934 - 1996